Slimming Drugs Helpful in Stopping the Regeneration of Lung Cancer Cells: Singapore Scientists


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A group of researchers in Singapore might have come across a surprising way of treating lung cancer with the help of slimming drugs. The medical research scientists from the CSI (Cancer Science Institute) of Singapore found that after their in-depth 5-year study which was focused on finding a cure for non-small cell lung cancer –the most common form of lung cancer, they have come to the observation that slimming drugs could be helpful in stopping the regeneration of the lung cancer cells.

The scientists at the National University of Singapore & Beth Israel Deaconess Medical Center located in America have come up with the finding that lung cancer cells tend to produce a protein referred to as FASN (Fatty Acid Synthase).

This protein enzyme is responsible for facilitating the production of palmitate –a form of saturated fatty acid that is believed to make the lung cancer cells unaffected to the drug-induced during chemotherapy known as “TKI (Tyrosine Kinase Inhibitors)”. Due to this, the cancer cells that are not killed by TKI get the chance to reproduce themselves leading to the growth of the tumor all over again.

A senior research scientist named Dr. Azhar Ali at CSI stated that in normal body cells, there is no production of FASN. However, in comparison to the normal body cells, the cancer cells tend to grow at an exponential rate. The cancer cells receive the energy from the fatty acids and produce FASN protein.

Ending the finding of the study on a positive note, the medical research team concluded that the possible solution to the stopping of the regeneration of the lung cancer cells might lie in a particular weight loss drug named as “Orlistat”. After a series of experiments, Orlistat was found to be blocking the