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Hippocampus-Avoidance Whole-brain Radiotherapy

Cancer takes many innocent lives, so is the brain tumor. 120 types of brain tumors have been killing people annually and even after treatment survival is of one year. In Canada, 27 people are given this bad news daily. One of the methods to fight this cancer is radiation treatment. Strong energy rays, like X-rays, [...]

Cancer takes many innocent lives, so is the brain tumor. 120 types of brain tumors have been killing people annually and even after treatment survival is of one year. In Canada, 27 people are given this bad news daily.

One of the methods to fight this cancer is radiation treatment. Strong energy rays, like X-rays, are used to kill brain tumors but during treatment, such rays cause greater loss. The person starts to lose cognitive abilities as healthy regions of his brain also confront hazardous rays. Hippocampus is responsible for the cognitive function and if it’s saved from radiations, the treatment by rays would be really influential.

Memantine is a drug that is given along radiation therapy to the brain tumor patients. It’s not a cure to the disease but it helps to improve the cognitive abilities of a person. It’s very effective in Alzheimer’s where it treats moderate to severe symptoms.

Researchers at Mayo Clinic tested the cure by hippocampus-avoidance whole-brain radiotherapy and whole-brain radiotherapy, both along memantine. 518 patients were tested in the trial with an average age of 61. 5 years. The results showed that the group who received hippocampal-avoidance whole-brain radiotherapy along memantine was in a greater benefit as cognitive abilities were better preserved in them. Traditional radiotherapy provided a lesser cure and overall survival. The effectiveness of the new kind of radiotherapy was independent of age, and neurocognitive functions were cured in old aged people regardless of their age.

Hippocampus-avoidance whole-brain radiotherapy could prove itself as a hand to those drowning. Because there is a 20-40% chance that cancer might spread to the brain and no really effective cures came out yet. So this approach to treat brain tumors might have a noticeable impact on the lives of brain tumor patients.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4239301/

https://www.medicalnewsbulletin.com/new-brain-cancer-treatment-cognitive-function/

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