A one-year regimen for women shows evidence of reducing proteins associated with cancer.
Being overweight and having a sedentary lifestyle have long been proven to increase the risk of developing cancer. A new study published in the American Association for Cancer Research journal highlights just how important weight loss and physical exercise can be.
A number 439 women, with ages between 50 and 75, were recruited to take part in a trial that focused on tracking several markers connected with cancer. These included: vascular endothelial growth factor, plasminogen activator inhibitor-1 (PAI-1), and pigment epithelium-derived factor (PEDF).
They were divided into four groups, one that continued without changes in their routine (control group), another was recommended to follow a certain diet, a third one was recommended an exercise plan, and lastly, one that was put on both diet and exercise schedule.
The results were somewhat unexpected. While all three groups that adhered to the regimen showed weight loss, there was a significant difference in markers of Angiogenesis. Generally, a healthy process that helps with wound healing, the formation of new blood vessels and tissue, angiogenesis can also reveal signs of tumors in the body.
Participants that followed a diet and exercised regularly, showed significantly greater reductions in levels of PAI-1 compared to the control group (about 19%), over the course of the one-year medical trial.
Both groups, diet and diet + exercise, had considerable improvements when it came to PEDF and VEGF too (around 10%).
Quite surprisingly, the group that only exercised and continued with previous eating habits, displayed very little improvement.
The results show that just physical exercise, which was considered a valid solution for reducing the risk of cancer, is not enough. Dietary weight loss is more important than previously believed.
While physical training has numerous health benefits, not only helping with weight loss, a diet will be more effective at taking away the extra weight and keep you safe when it comes to the risk of cancer.