A vaccine for the experimental treatment of bone cancer in dogs can help in providing a road map for the human version of the bone cancer treatment at the same time, a study reports.
Every year, over 10,000 cases of bone cancer in dogs come up in the United States. However, the disease is not so common in human beings. Only around 800 to 900 cases of bone cancer in human beings come up every year. Almost half of such cases belong to that of children and teens.
A recent study reveals that vaccine created from the tumor of a dog can target the specific cancer cells and eliminate the overall need for chemotherapy. Chemotherapy is known to cause a host of side effects on the body. As such, a team of researchers at the University of Missouri believe that this study could serve to be revolutionary in helping patients with bone cancer.
Jeffrey Bryan –Professor of Oncology at the College of Veterinary Medicine, explains, “A vaccine that is made out of the tumor of a dog (dog’s immune system) can be helpful in the study.” Jeffrey is also the Director at the Comparative Oncology Radiobiology & Epigenetics Laboratory at the University of Missouri.
Dogs that have received the vaccination were known to have over 400 days of remission. This is quite a comparison to the standard 270 days of remission in case of the dogs receiving chemotherapy. This was observed in a separate study conducted at the National Cancer Institute in the United States of America.
Bryan further stated, “The dogs under the study received no chemotherapy. They only received immunotherapy for the given treatment. It is going to be the first time in which dogs having bone cancer (osteosarcoma) have experienced extended survival without receiving painful chemotherapy treatment. As such, this turns out to be quite exciting.”
In the study, the treatment makes use of the lymphocytes of the dog with cancer. Lymphocytes are specialized immune cells that are capable of recognizing wherein pathogens tend to hide in the body. Then, lymphocytes kill the cells that harbor the respective pathogens in the body. After removing the tumor from the dog’s body, the researchers created a vaccine by making use of the tumor cells of the dog for stimulating anti-cancer lymphocytes. The vaccine is then transfused into the dog.
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