A team of researchers at Georgetown University were recently studying a specific protein for cancer research. In the given research, the researchers were surprised at the protein turned out to be a powerful metabolism regulator. The study was published in the Scientific Reports.
The forced infusion of the natural protein “FGFBP3” in obese mice turned out significant in reducing the overall fat mass even after genetically adapted to eating continuously. The all-new revolutionary study suggests that it could serve as a major breakthrough in reversing the disorders that are usually associated with metabolic syndromes like Type 2 Diabetes and fatty liver diseases.
FGFBP3 serves to be a natural protein. As per the clinical trials of the study, the researchers suggest that the recombinant form of human BP3 might start only after the final round of the pre-clinical trials on mice. Around 8 treatments that were conducted with the protein FGFBP3 over the course of 18 days were successful in reducing the fat amongst obese mice by over one-third.
The treatments that were carried out with FGFBP3 have also reduced the number of disorders related to obesity in mice. Some of the common obesity-related disorders that showed significant reduction was hyperglycemia and others. The treatments were successful in eliminating the fatty livers. Moreover, the clinical & microscopic examinations on mice showed no side effects at the same time.
In the current scenario, over 650 million people are suffering from obesity and its related disorders across the globe. Obesity serves to be a major driver of the common problems hyperglycemia, hypertension, elevated lipids, glucose intolerance, insulin intolerance, and others. FGF –Fibroblast Growth Factor proteins are commonly found in organisms – from the humans to worms. These natural proteins are usually involved in a wide range of biological processes including responses to injury, wound healing, regulation of cell growth, and some proteins might even act as hormones in some cases.
The Chaperone proteins including BP1, BP2, and BP3 usually bind themselves to the FGF proteins for enhancing the overall activity. In the given study, the scientists reveal that additional research is required before determining the effectiveness of the natural protein FGFBP3 in reducing obesity in human beings as well.
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